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NFL Week 3

NFL

San Francisco

v


Arizona

Monday, September 22nd, 2025
6:25 AM (Timezone: Australia/Sydney)
Levi's Stadium (Santa Clara, California)

Introduction

This match centre provides fixture details, team news, bookmaker odds, form guides and team statistics for the NFL Week 3 clash between the San Francisco 49ers and the Arizona Cardinals. You can view other fixtures for this round in the NFL match centre.

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MarketSelectionOpenCurrent
H2H San Francisco
Arizona
1.53
2.50
1.80
2.00
Line San Francisco
Arizona
-3.5  1.93
+3.5  1.88
-2.5  2.00
+2.5  1.80
Total Over
Under
40.5  1.34
40.5  3.20
40.5  1.62
40.5  2.30

Compare bookmaker odds for NFL Week 3

Member Tipping

The # and % columns denote the number of tippers for each selection, not the number of units tipped. Submit or edit your tips for this fixture.

All Tippers

Selection #%
San Francisco
Arizona
0
0
0.0%
0.0%
San Francisco (-2.5)
Arizona (+2.5)
0
0
0.0%
0.0%
Over 40.5
Under 40.5
0
0
0.0%
0.0%

My Favourite Tippers

Selection #%
San Francisco
Arizona
0
0
0.0%
0.0%
San Francisco (-2.5)
Arizona (+2.5)
0
0
0.0%
0.0%
Over 40.5
Under 40.5
0
0
0.0%
0.0%

San Francisco Supporters

Selection #%
San Francisco
Arizona
0
0
0.0%
0.0%
San Francisco (-2.5)
Arizona (+2.5)
0
0
0.0%
0.0%
Over 40.5
Under 40.5
0
0
0.0%
0.0%

Arizona Supporters

Selection #%
San Francisco
Arizona
0
0
0.0%
0.0%
San Francisco (-2.5)
Arizona (+2.5)
0
0
0.0%
0.0%
Over 40.5
Under 40.5
0
0
0.0%
0.0%

Form Guide: San Francisco 49ers

Date (y-m-d)FixtureResultScore
2025-09-15New Orleans vs. San FranciscoWin21-26
2025-09-08Seattle vs. San FranciscoWin13-17
2025-01-06Arizona vs. San FranciscoLoss47-24
2024-12-31San Francisco vs. DetroitLoss34-40
2024-12-23Miami vs. San FranciscoLoss29-17
2024-12-13San Francisco vs. LA RamsLoss6-12
2024-12-09San Francisco vs. ChicagoWin38-13
2024-12-02Buffalo vs. San FranciscoLoss35-10
2024-11-25Green Bay vs. San FranciscoLoss38-10
2024-11-18San Francisco vs. SeattleLoss17-20
2024-11-11Tampa Bay vs. San FranciscoWin20-23
2024-10-28San Francisco vs. DallasWin30-24

Form Guide: Arizona Cardinals

Date (y-m-d)FixtureResultScore
2025-09-15Arizona vs. CarolinaWin27-22
2025-09-08New Orleans vs. ArizonaWin13-20
2025-01-06Arizona vs. San FranciscoWin47-24
2024-12-29LA Rams vs. ArizonaLoss13-9
2024-12-23Carolina vs. ArizonaLoss36-30 (OT)
2024-12-16Arizona vs. New EnglandWin30-17
2024-12-09Arizona vs. SeattleLoss18-30
2024-12-02Minnesota vs. ArizonaLoss23-22
2024-11-25Seattle vs. ArizonaLoss16-6
2024-11-11Arizona vs. NY JetsWin31-6
2024-11-04Arizona vs. ChicagoWin29-9
2024-10-28Miami vs. ArizonaWin27-28

Head-to-Head Results

Date (y-m-d)FixtureScore
2025-01-06Arizona vs. San Francisco47-24
2024-10-07San Francisco vs. Arizona23-24
2023-12-18Arizona vs. San Francisco29-45
2023-10-02San Francisco vs. Arizona35-16
2023-01-09San Francisco vs. Arizona38-13
2022-11-22Arizona vs. San Francisco10-38
2021-11-08San Francisco vs. Arizona17-31
2021-10-11Arizona vs. San Francisco17-10
2020-12-27Arizona vs. San Francisco12-20
2020-09-14San Francisco vs. Arizona20-24
2019-11-18San Francisco vs. Arizona36-26
2019-11-01Arizona vs. San Francisco25-28

Note: only league fixtures are included, not
pre-season or cup fixtures.

Performance Guide: San Francisco 49ers

 Last 12 Monthsvs. Arizona
H2H
Betting
Home
Games
All
Games
Home
Games
All
Games
Streak2 losses2 wins1 loss2 losses
Record3-0-57-0-1010-0-919-0-19
Value$-3.82$-6.90$-5.00$-3.24
Record as Fav3-0-47-0-69-0-514-0-8
Value as Fav$-2.82$-2.90$-2.85$-4.23
Record as Dog0-0-10-0-41-0-45-0-11
Value as Dog$-1.00$-4.00$-2.15$0.99
Line
Betting
Home
Games
All
Games
Home
Games
All
Games
Streak2 losses1 loss1 loss2 losses
Record3-0-55-0-127-1-1119-1-18
Value$-2.27$-7.55$-4.54$-0.43
Record as Fav3-0-45-0-85-1-89-1-12
Value as Fav$-1.27$-3.55$-3.42$-3.77
Record as Dog0-0-10-0-42-0-310-0-6
Value as Dog$-1.00$-4.00$-1.12$3.34
Winning Margin
Betting
Home
Games
All
Games
Home
Games
All
Games
1-12 wins1549
13+ wins22610
1-12 losses57816
13+ losses0313
1-7 win1426
8+ win23813
1-7 loss45411
8+ loss1558
Total Score
Betting
Home
Games
All
Games
Home
Games
All
Games
O/U Streak1 over1 over1 under1 over
O/U Record4-0-410-0-710-0-920-0-18
Overs Value$-0.36$2.05$0.14$0.34
Unders Value$-0.36$-4.05$-1.68$-3.31

Performance Guide: Arizona Cardinals

 Last 12 Monthsvs. San Francisco
H2H
Betting
Away
Games
All
Games
Away
Games
All
Games
Streak1 win3 wins1 win2 wins
Record3-0-59-0-89-0-1019-0-19
Value$-0.08$1.07$2.61$-0.11
Record as Fav1-0-25-0-44-0-111-0-5
Value as Fav$-1.58$-1.53$1.31$-0.67
Record as Dog2-0-34-0-45-0-98-0-14
Value as Dog$1.50$2.60$1.30$0.56
Line
Betting
Away
Games
All
Games
Away
Games
All
Games
Streak2 wins4 wins1 win2 wins
Record5-0-311-0-611-1-718-1-19
Value$1.50$3.90$3.25$-2.28
Record as Fav1-0-25-0-43-0-26-0-10
Value as Fav$-1.18$0.36$0.83$-4.38
Record as Dog4-0-16-0-28-1-512-1-9
Value as Dog$2.68$3.54$2.42$2.10
Winning Margin
Betting
Away
Games
All
Games
Away
Games
All
Games
1-12 wins35816
13+ wins0413
1-12 losses4649
13+ losses12610
1-7 win35411
8+ win0458
1-7 loss3426
8+ loss24813
Total Score
Betting
Away
Games
All
Games
Away
Games
All
Games
O/U Streak2 unders1 over1 under1 over
O/U Record2-2-47-2-810-0-920-0-18
Overs Value$-2.18$-2.14$0.14$0.34
Unders Value$2.98$1.61$-1.68$-3.31

Further Analysis: San Francisco 49ers

RecordOn the Back
of a Win
On the Back
of a Loss
H2H Record2-0-45-0-6
H2H Betting Value$-3.37$-3.53
Line Record0-0-65-0-6
Line Betting Value$-6.00$-1.55
Over/Under Record1-0-59-0-2
Overs Betting Value$-4.13$6.18
Unders Betting Value$3.55$-7.59

 

Further Analysis: Arizona Cardinals

RecordOn the Back
of a Win
On the Back
of a Loss
H2H Record5-0-44-0-4
H2H Betting Value$0.54$0.53
Line Record5-0-46-0-2
Line Betting Value$0.40$3.50
Over/Under Record3-1-54-1-3
Overs Betting Value$-2.77$0.64
Unders Betting Value$2.89$-1.27

 

Value Guides:

TeamMarketLast 6Last 12Last 18
San FranciscoH2H$-2.91$-4.57$-7.90
Line$-4.19$-6.37$-8.55
Overs$1.60$1.32$1.05
Unders$-2.59$-2.86$-3.14
ArizonaH2H$-0.33$0.32$1.98
Line$3.40$5.04$4.85
Overs$1.14$-0.04$-1.23
Unders$-0.84$-0.11$0.61

The above figures represent the net profit from wagering
$1.00 on the associated selection each game.

Where applicable, the line and O/U figures start from
the dates provided in the Notes section below the
Performance Guide.

Notes

1. The Value represent the net profit from wagering $1.00 on the associated selection each game.
2. For the 'Last 12 Months' figures the H2H records date back to September, 2024. The line records date back to September, 2024. The O/U records date back to September, 2024.
3. The H2H records between San Francisco 49ers and Arizona Cardinals date back to September, 2006. The line records between the two opponents date back to September, 2006. The O/U records between the two opponents date back to September, 2006.
4. Where applicable, in the Value Guide for the last 6, 12 and 18, games, the actual lookback period is limited by the earliest line and O/U dates stated in Note 2 above.

NFL Resources

The interactive NFL form guide enables you to view overall as well as home and away form guides for the league. You can also filter by strength of opponent.

The NFL betting value index ranks each team based on their betting value in the head-to-head market.

The NFL Elo ratings tool calculates the Elo ratings of each team using the parameters of your choosing.

The NFL home-field advantage analysis compares each team's home and away records.

The NFL line betting table ranks each team based on how frequently they have covered the line this season. Figures are shown for home, away and all fixtures.

The NFL predictability index ranks each team based on the predictability of their score lines using pre-game bookmaker lines. Figures are shown for home, away and all fixtures.

The NFL score statistics provides points for, points against, points difference plus total score statistics for the current season. Averages for home games, away games and all games are provided.

The NFL stadium analysis provides a range of statistics for each team at each stadium.

The NFL table displays league table/ladder data for the date range of your choosing.

The NFL winning margins page provides winning margin data for the league as well as for specific teams at home and/or away.

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